WebFeb 22, 2024 · Since FLI1 regulates the expression of its target genes by binding to their promoter regions, we explored whether it directly modulated the expression of TIE1, which has been reported to promote XPC-dependent nucleotide excision repair (NER) and chemotherapy resistance . hTFtarget ChIP-seq database also indicated that FLI1 might ... WebApr 10, 2024 · In addition to exploring and analyzing the genomic and epigenetic regulation mechanism of COPZ1 gene expression, we also analyzed the correlation between COPZ1 expression level and its potential regulated transcription factors. One hundred and seventeen potential transcription factors of COPZ1 were downloaded from the hTFtarget …
The transcription factor USF1 promotes glioma cell invasion and ...
WebWelcome to our hTFtarget. Transcription factors (TFs) as key regulators could modulate the expression of target genes by binding to specific DNA sequences of their promoter (s) or … WebFeb 3, 2024 · More recently, the gene transcription regulation database (GTRD), an integrated database, can also be used for TF-targeted gene analysis in knockout, knockdown, ... TP53, and ZEB1 was obtained from an open resource hTFtarget with default setting and TFoTF with the 75th percentile value of the corresponding score as the cut … online ttd darshan
Target Finder of Transcription Factor (TFoTF): a novel tool to …
WebNov 16, 2024 · In this study, we constructed a database named hTFtarget, which integrated huge human TF target resources (7,190 ChIP-Seq samples of 659 TFs and high … WebJan 19, 2024 · The bioinformatics databases (hTFtarget, starBase and TargetScan) were used to predict the upstream and downstream regulatory molecules of E2F7. Then the binding relationships between E2F7 and regulatory molecules were verified by ChIP and dual-luciferase reporter assay. qRT-PCR and western blot were used to detect the … WebApr 1, 2024 · The HOCOMOCO , JASPAR , TRANSFAC v2024 , and TFBSbank databases focus on the collection and discovery of the motif profiles for TFBSs, while TRRUST elucidates TF–target interactions using text mining . hTFtarget is the only currently available database integrating various resources to provide an almost one-stop solution in … online tsrtc