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WebMay 7, 2024 · How Benadryl makes sleeping easier Antihistamines stop allergic reactions by blocking excess production of histamine in the immune system. Some also block histamine release in the brain. The... WebApr 7, 2024 · Benadryl is commonly sold in 25 mg doses to treat an allergic reaction. For sleep, 50 mg of diphenhydramine is commonly recommended. Is is safe to use diphenhydramine for sleep every night? Diphenhydramine is a nonaddictive sleep aid. However, it is only recommended for short-term treatment of insomnia. headquarter images
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