Thiazide diuretics and hip fractures
WebVertebral fracture is the most common type of osteoporotic fracture. While thiazide diuretics, which are commonly prescribed for the treatment of hypertension, decrease calciuria, they may also induce hyponatremia, which has been associated with increased vertebral fracture risk. WebBackground Thiazide diuretics are one of the most commonly prescribed antihypertensive agents worldwide. Thiazides reduce urinary calcium excretion. Chronic ingestion of …
Thiazide diuretics and hip fractures
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WebThiazide diuretics reduce urinary calcium and may inhibit bone resorption, and hence may help to attenuate age-related bone loss and to lower the risk of osteoporotic fracture. We … Web30 Nov 2016 · Many drugs can affect bone metabolism. As examples, heparin, warfarin, cyclosporine, glucocorticoids, medroxyprogesterone acetate, cancer drugs, and thyroid …
Web1 Sep 1997 · Thiazide diuretics appear to reduce the risk of hip fracture based on observational studies, and randomized controlled trials are needed to confirm these findings. 59 PDF Antihypertensive drugs demonstrate varying levels of hip fracture risk: A systematic review and meta-analysis. WebStudies looked for an association between thiazide diuretic use and hip fracture. The majority of included studies have low to moderate risk of bias. Thiazide diuretic use was …
WebIn the subsequent four years, 242 subjects had hip fractures. The incidence rates of hip fracture were lower among thiazide users than nonusers in each community; the Mantel … Web27 Sep 2024 · Europe PMC is an archive of life sciences journal literature.
WebFor instance, in case-controlled trials, the use of thiazides reduced the rate of loss in calcaneal bone density by 49% compared to controls and the relative risk of hip fracture was halved by exposure to thiazides for more than 6 years [67].
Web1 Mar 2004 · In an earlier analysis in The Rotterdam Study [17], for instance, it was investigated whether thiazide diuretics protect against hip fracture, thanks to their … unstitched fabric for menWebA Cochrane review found tentative evidence that thiazide exposure was associated with a reduced risk of hip fracture. A secondary analysis of data from the ALLHAT study found that chlortalidone reduced risk of hip and pelvis fracture. ... As with other thiazide diuretics, chlortalidone crosses the placenta and is excreted in breast milk ... recipes with noodles and ground beefWeb11 Sep 2024 · Thiazide diuretics were not associated with decreased hip fractures, but uncertainty was higher for this outcome. Meta-analysis could not be conducted for BMD because of increased heterogeneity. Our … unstitched designer suit materialWebAn alleged association of chronic use of thiazide diuretics with an increased risk of bone fragility fractures has been highlighted by a relatively recent prospective cohort study. However, the concept that thiazides exert a beneficial effect on osteoporosis is still a predominant view. recipes with not many ingredientsWeb5 Oct 2011 · Search life-sciences literature (Over 39 million articles, preprints and more) recipes with no sugar or flourWeb7 Dec 2024 · Thiazide users with hyponatremia have a higher risk of fracture than thiazide users without hyponatremia. The fracture-protective effect of thiazide is attenuated by TAH. Introduction... recipes with nutella111WebCurrent thiazide users have a 20% reduction in fracture risk and that long-term use may reduce fractures by a similar amount. In the absence of suitable randomised controlled … unstitched fancy suits